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"trouble" is also used as a crossword clue. If that's what you saw, the answer is often inconvenience (13 letters).
Definitions
Difficulty, distress, or a cause of concern.
Word origin
Verb is from Middle English troublen, trouble, borrowed from Old French troubler, trobler, trubler, metathetic variants of tourbler, torbler, turbler, from Vulgar Latin *turbulō, from Latin turbula (“disorderly group, a little crowd or people”), diminutive of turba (“stir; crowd”). The noun is from Middle English trouble, troble, from Old French troble, from the verb.
Used in a sentence
“He was in trouble when the rain started.”
“The trouble was a leaking brake line.”
“The bridge column magnified the trouble with a slight tilt in the wrong direction.”
Source: Wiktionary, CC BY-SA 4.0
Used as a crossword answer3 curated clues
01“Problem or difficulty”7 letters
02“Difficulty or problems”7 letters
03“Difficulty or worry”7 letters
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