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"adverse" is also used as a crossword clue. If that's what you saw, the answer is often unfavorable (11 letters).
Definitions
in an opposing direction
Word origin
First attested around 1374, from Old French avers (French adverse), from Latin adversus (“turned against”), past participle of advertere, from ad- (“to”) + vertere (“to turn”). See also versus.
Used in a sentence
“adverse criticism”
“adverse weather”
“Happy were it for us all if we bore prosperity as well and wisely as we endure an adverse fortune.”
Source: Wiktionary, CC BY-SA 4.0
Used as a crossword answer2 curated clues
01“Working against”7 letters
02“Unfavorable”7 letters
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