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"estranged" is also used as a crossword clue. If that's what you saw, the answer is often alienated (9 letters).
Definitions
caused to be unloved
Used in a sentence
“He managed to become estranged from all of his friends.”
“She estranged her husband by not talking to him for over a year.”
Source: Wiktionary, CC BY-SA 4.0
Used as a crossword answer1 curated clues
01“Alienated”9 letters
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